Recent Publications from BIIC Members

Pancreatic beta cell mass PET imaging and quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in rodent models of diabetes.
Role of phospholipase Cε in physiological phosphoinositide signaling networks.
Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans.
Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol.
Epac2-dependent mobilization of intracellular Ca2+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in beta-cells of phospholipase C-epsilon knockout mice.
Hyperglucagonemia precedes a decline in insulin secretion and causes hyperglycemia in chronically glucose-infused rats.
Cytoplasmic Polyadenylation Element Binding Protein Deficiency Stimulates PTEN and Stat3 mRNA Translation and Induces Hepatic Insulin Resistance.
Prevalence of hepatitis C virus genotype 1a in Japan and correlation of mutations in the NS5A region and single-nucleotide polymorphism of interleukin-28B with the response to combination therapy with pegylated-interferon-alpha 2b and ribavirin.
Rates of insulin secretion in INS-1 cells are enhanced by coupling to anaplerosis and Kreb's cycle flux independent of ATP synthesis.
CT-PET weighted image fusion for separately scanned whole body rat.

You are hereRecent Publications of Members of the Boston Ithaca Islet Club

Recent Publications of Members of the Boston Ithaca Islet Club

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2009

Heart E, Cline GW, Collis LP, Pongratz RL, Gray JP, Smith PJ. 2009. Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion. Am J Physiol Endocrinol Metab. 296(6):E1354-62. Abstract

Peyot ML, Gray JP, Lamontagne J, Smith PJ, Holz GG, Madiraju SR, Prentki M, Heart E. 2009. Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells. PLoS One. 4(7):e6221. Abstract

2008

Pethig R, Menachery A, Heart E, Sanger RH, Smith PJ. 2008. Dielectrophoretic assembly of insulinoma cells and fluorescent nanosensors into three-dimensional pseudo-islet constructs. IET Nanobiotechnol. 2(2):31. Abstract

2007

Heart E, Smith PJ. 2007. Rhythm of the beta-cell oscillator is not governed by a single regulator: multiple systems contribute to oscillatory behavior. Am J Physiol Endocrinol Metab. 292(5):E1295-300. Abstract

Gray JP, Heck DE, Mishin V, Smith PJ, Hong JY, Thiruchelvam M, Cory-Slechta DA, Laskin DL, Laskin JD. 2007. Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an NAD(P)H:paraquat oxidoreductase: identification of the enzyme as thioredoxin reductase. J Biol Chem. 282(11):7939-49. Abstract

Heart E, Yaney GC, Corkey RF, Schultz V, Luc E, Liu L, Deeney JT, Shirihai O, Tornheim K, Smith PJ, Corkey BE. 2007. Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose. Biochem J. 403(1):197-205. Abstract

2005

Twig G, Graf SA, Messerli MA, Smith PJ, Yoo SH, Shirihai OS. 2005. Synergistic amplification of beta-amyloid- and interferon-gamma-induced microglial neurotoxic response by the senile plaque component chromogranin A. Am J Physiol Cell Physiol. 288(1):C169-75. Abstract

Pethig R, Jakubek LM, Sanger RH, Heart E, Corson ED, Smith PJ. 2005. Electrokinetic measurements of membrane capacitance and conductance for pancreatic beta-cells. IEE Proc Nanobiotechnol. 152(6):189-93. Abstract

2004

Katzman SM, Messerli MA, Barry DT, Grossman A, Harel T, Wikstrom JD, Corkey BE, Smith PJ, Shirihai OS. 2004. Mitochondrial metabolism reveals a functional architecture in intact islets of Langerhans from normal and diabetic Psammomys obesus. Am J Physiol Endocrinol Metab. 287(6):E1090-9. Abstract

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