Recent Publications from BIIC Members

Pancreatic beta cell mass PET imaging and quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in rodent models of diabetes.
Role of phospholipase Cε in physiological phosphoinositide signaling networks.
Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans.
Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol.
Epac2-dependent mobilization of intracellular Ca2+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in beta-cells of phospholipase C-epsilon knockout mice.
Hyperglucagonemia precedes a decline in insulin secretion and causes hyperglycemia in chronically glucose-infused rats.
Cytoplasmic Polyadenylation Element Binding Protein Deficiency Stimulates PTEN and Stat3 mRNA Translation and Induces Hepatic Insulin Resistance.
Prevalence of hepatitis C virus genotype 1a in Japan and correlation of mutations in the NS5A region and single-nucleotide polymorphism of interleukin-28B with the response to combination therapy with pegylated-interferon-alpha 2b and ribavirin.
Rates of insulin secretion in INS-1 cells are enhanced by coupling to anaplerosis and Kreb's cycle flux independent of ATP synthesis.
CT-PET weighted image fusion for separately scanned whole body rat.

You are hereRecent Publications of Members of the Boston Ithaca Islet Club

Recent Publications of Members of the Boston Ithaca Islet Club

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2008

Liu Z, Habener JF. 2008. Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation. J Biol Chem. 283(13):8723-35. Abstract

Elahi D, Egan JM, Shannon RP, Meneilly GS, Khatri A, Habener JF, Andersen DK. 2008. GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity (Silver Spring). 16(7):1501-9. Abstract

Stanojevic V, Habener JF, Holz GG, Leech CA. 2008. Cytosolic adenylate kinases regulate K-ATP channel activity in human beta-cells. Biochem Biophys Res Commun. 368(3):614-9. Abstract

2007

Rukstalis JM, Habener JF. 2007. Snail2, a mediator of epithelial-mesenchymal transitions, expressed in progenitor cells of the developing endocrine pancreas. Gene Expr Patterns. 7(4):471-9. Abstract

Yano T, Liu Z, Donovan J, Thomas MK, Habener JF. 2007. Stromal cell derived factor-1 (SDF-1)/CXCL12 attenuates diabetes in mice and promotes pancreatic beta-cell survival by activation of the prosurvival kinase Akt. Diabetes. 56(12):2946-57. Abstract

2006

Ubeda M, Rukstalis JM, Habener JF. 2006. Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity. J Biol Chem. 281(39):28858-64. Abstract

List JF, He H, Habener JF. 2006. Glucagon-like peptide-1 receptor and proglucagon expression in mouse skin. Regul Pept. 134(2-3):149-57. Abstract

Rukstalis JM, Habener JF. 2006. Islets break off from the mainland. Nat Med. 12(3):273-4.

Rukstalis JM, Ubeda M, Johnson MV, Habener JF. 2006. Transcription factor snail modulates hormone expression in established endocrine pancreatic cell lines. Endocrinology. 147(6):2997-3006. Abstract

2005

Habener JF, Kemp DM, Thomas MK. 2005. Minireview: transcriptional regulation in pancreatic development. Endocrinology. 146(3):1025-34. Abstract

Gragnoli C, Milord E, Habener JF. 2005. Linkage study of the glucagon receptor gene with type 2 diabetes mellitus in Italians. Metabolism. 54(6):786-7. Abstract

Lechner A, Nolan AL, Blacken RA, Habener JF. 2005. Redifferentiation of insulin-secreting cells after in vitro expansion of adult human pancreatic islet tissue. Biochem Biophys Res Commun. 327(2):581-8. Abstract

Gragnoli C, Stanojevic V, Gorini A, Von Preussenthal GM, Thomas MK, Habener JF. 2005. IPF-1/MODY4 gene missense mutation in an Italian family with type 2 and gestational diabetes. Metabolism. 54(8):983-8. Abstract

2004

Lechner A, Yang YG, Blacken RA, Wang L, Nolan AL, Habener JF. 2004. No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivo. Diabetes. 53(3):616-23. Abstract

List JF, Habener JF. 2004. Glucagon-like peptide 1 agonists and the development and growth of pancreatic beta-cells. Am J Physiol Endocrinol Metab. 286(6):E875-81. Abstract

Ubeda M, Kemp DM, Habener JF. 2004. Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic beta-cells. Endocrinology. 145(6):3023-31. Abstract

Stanojevic V, Habener JF, Thomas MK. 2004. Pancreas duodenum homeobox-1 transcriptional activation requires interactions with p300. Endocrinology. 145(6):2918-28. Abstract

Ogawa N, List JF, Habener JF, Maki T. 2004. Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4. Diabetes. 53(7):1700-5. Abstract

Gragnoli C, Menzinger Von Preussenthal G, Habener JF. 2004. Triple genetic variation in the HNF-4alpha gene is associated with early-onset type 2 diabetes mellitus in a philippino family. Metabolism. 53(8):959-63. Abstract

Schmitt-Ney M, Habener JF. 2004. Cell-density-dependent regulation of actin gene expression due to changes in actin treadmilling. Exp Cell Res. 295(1):236-44. Abstract

Habener JF. 2004. A perspective on pancreatic stem/progenitor cells. Pediatr Diabetes. 5 Suppl 2:29-37. Abstract

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