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Recent Publications of Members of the Boston Ithaca Islet Club


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2009
Emamaullee JA, Merani S, Toso C, Kin T, Al-Saif F, Truong W, Pawlick R, Davis J, Edgar R, Lock J, Bonner-Weir S, Knudsen LB, Shapiro AM.  2009.  Porcine marginal mass islet autografts resist metabolic failure over time and are enhanced by early treatment with liraglutide. Endocrinology. Abstract
Kikugawa R, Katsuta H, Akashi T, Yatoh S, Weir GC, Sharma A, Bonner-Weir S.  2009.  Differentiation of COPAS-sorted non-endocrine pancreatic cells into insulin-positive cells in the mouse. Diabetologia. Abstract
Nagaya M, Katsuta H, Kaneto H, Bonner-Weir S, Weir GC.  2009.  Adult mouse intrahepatic biliary epithelial cells induced in vitro to become insulin-producing cells. J Endocrinol. Abstract
Borowiec M, Liew CW, Thompson R, Boonyasrisawat W, Hu J, Mlynarski WM, El Khattabi I, Kim SH, Marselli L, Rich SS, Krolewski AS, Bonner-Weir S, Sharma A, Sale M, Mychaleckyj JC, Kulkarni RN, Doria A.  2009.  Mutations at the BLK locus linked to maturity onset diabetes of the young and {beta}-cell dysfunction. Proc Natl Acad Sci U S A. Abstract
Kondo T, El Khattabi I, Nishimura W, Laybutt DR, Geraldes P, Shah S, King G, Bonner-Weir S, Weir G, Sharma A.  2009.  p38 MAPK is a major regulator of MafA protein stability under oxidative stress. Mol Endocrinol. 23(8):1281-90. Abstract
Marselli L, Sgroi DC, Bonner-Weir S, Weir GC.  2009.  Laser Capture Microdissection of Human Pancreatic beta-Cells and RNA Preparation for Gene Expression Profiling. Methods Mol Biol. 560:87-98. Abstract
2008
Larade K, Jiang Z, Zhang Y, Wang W, Bonner-Weir S, Zhu H, Bunn HF.  2008.  Loss of Ncb5or results in impaired fatty acid desaturation, lipoatrophy, and diabetes. J Biol Chem. 283(43):29285-91. Abstract
Koulmanda M, Bhasin M, Hoffman L, Fan Z, Qipo A, Shi H, Bonner-Weir S, Putheti P, Degauque N, Libermann TA, Auchincloss H. J, Flier JS, Strom TB.  2008.  Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice. Proc Natl Acad Sci U S A. 105(42):16242-7. Abstract
Akashi T, Shigematsu H, Hamamoto Y, Iwasaki H, Yatoh S, Bonner-Weir S, Akashi K, Weir GC.  2008.  Bone marrow or foetal liver cells fail to induce islet regeneration in diabetic Akita mice. Diabetes Metab Res Rev. 24(7):585-90. Abstract
Bonner-Weir S, O'Brien TD.  2008.  Islets in type 2 diabetes: in honor of Dr. Robert C. Turner. Diabetes. 57(11):2899-904.
Marselli L, Thorne J, Ahn YB, Omer A, Sgroi DC, Libermann T, Otu HH, Sharma A, Bonner-Weir S, Weir GC.  2008.  Gene expression of purified beta-cell tissue obtained from human pancreas with laser capture microdissection. J Clin Endocrinol Metab. 93(3):1046-53. Abstract
Bonner-Weir S, Inada A, Yatoh S, Li WC, Aye T, Toschi E, Sharma A.  2008.  Transdifferentiation of pancreatic ductal cells to endocrine beta-cells. Biochem Soc Trans. 36(Pt 3):353-6. Abstract
Nishimura W, Rowan S, Salameh T, Maas RL, Bonner-Weir S, Sell SM, Sharma A.  2008.  Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice. Dev Biol. 314(2):443-56. Abstract
Inada A, Nienaber C, Katsuta H, Fujitani Y, Levine J, Morita R, Sharma A, Bonner-Weir S.  2008.  Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc Natl Acad Sci U S A. 105(50):19915-9. Abstract
de Koning EJ, Bonner-Weir S, Rabelink TJ.  2008.  Preservation of beta-cell function by targeting beta-cell mass. Trends Pharmacol Sci. 29(4):218-27. Abstract
2007
King AJ, Fernandes JR, Hollister-Lock J, Nienaber CE, Bonner-Weir S, Weir GC.  2007.  Normal relationship of beta- and non-beta-cells not needed for successful islet transplantation. Diabetes. 56(9):2312-8. Abstract
Laybutt DR, Hawkins YC, Lock J, Lebet J, Sharma A, Bonner-Weir S, Weir GC.  2007.  Influence of diabetes on the loss of beta cell differentiation after islet transplantation in rats. Diabetologia. 50(10):2117-25. Abstract
Yatoh S, Akashi T, Chan PP, Kaneto H, Sharma A, Bonner-Weir S, Weir GC.  2007.  NeuroD and reaggregation induce beta-cell specific gene expression in cultured hepatocytes. Diabetes Metab Res Rev. 23(3):239-49. Abstract
Xu G, Kaneto H, Laybutt DR, Duvivier-Kali VF, Trivedi N, Suzuma K, King GL, Weir GC, Bonner-Weir S.  2007.  Downregulation of GLP-1 and GIP receptor expression by hyperglycemia: possible contribution to impaired incretin effects in diabetes. Diabetes. 56(6):1551-8. Abstract
Yatoh S, Dodge R, Akashi T, Omer A, Sharma A, Weir GC, Bonner-Weir S.  2007.  Differentiation of affinity-purified human pancreatic duct cells to beta-cells. Diabetes. 56(7):1802-9. Abstract
Weir GC, Bonner-Weir S.  2007.  A dominant role for glucose in beta cell compensation of insulin resistance. J Clin Invest. 117(1):81-3. Abstract
Ahn YB, Xu G, Marselli L, Toschi E, Sharma A, Bonner-Weir S, Sgroi DC, Weir GC.  2007.  Changes in gene expression in beta cells after islet isolation and transplantation using laser-capture microdissection. Diabetologia. 50(2):334-42. Abstract
Koulmanda M, Budo E, Bonner-Weir S, Qipo A, Putheti P, Degauque N, Shi H, Fan Z, Flier JS, Auchincloss H. J, Zheng XX, Strom TB.  2007.  Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts. Proc Natl Acad Sci U S A. 104(32):13074-9. Abstract
Xue B, Kim YB, Lee A, Toschi E, Bonner-Weir S, Kahn CR, Neel BG, Kahn BB.  2007.  Protein-tyrosine phosphatase 1B deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance. J Biol Chem. 282(33):23829-40. Abstract
2006
Krishnamurthy J, Ramsey MR, Ligon KL, Torrice C, Koh A, Bonner-Weir S, Sharpless NE.  2006.  p16INK4a induces an age-dependent decline in islet regenerative potential. Nature. 443(7110):453-7. Abstract

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