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Recent Publications of Members of the Boston Ithaca Islet Club


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2009
Kikugawa R, Katsuta H, Akashi T, Yatoh S, Weir GC, Sharma A, Bonner-Weir S.  2009.  Differentiation of COPAS-sorted non-endocrine pancreatic cells into insulin-positive cells in the mouse. Diabetologia. Abstract
Nagaya M, Katsuta H, Kaneto H, Bonner-Weir S, Weir GC.  2009.  Adult mouse intrahepatic biliary epithelial cells induced in vitro to become insulin-producing cells. J Endocrinol. Abstract
Weir GC, Koulamnda M.  2009.  Control of inflammation with alpha1-antitrypsin: a potential treatment for islet transplantation and new-onset type 1 diabetes. Curr Diab Rep. 9(2):100-2.
Marselli L, Sgroi DC, Bonner-Weir S, Weir GC.  2009.  Laser Capture Microdissection of Human Pancreatic beta-Cells and RNA Preparation for Gene Expression Profiling. Methods Mol Biol. 560:87-98. Abstract
2008
Akashi T, Shigematsu H, Hamamoto Y, Iwasaki H, Yatoh S, Bonner-Weir S, Akashi K, Weir GC.  2008.  Bone marrow or foetal liver cells fail to induce islet regeneration in diabetic Akita mice. Diabetes Metab Res Rev. 24(7):585-90. Abstract
Boni-Schnetzler M, Thorne J, Parnaud G, Marselli L, Ehses JA, Kerr-Conte J, Pattou F, Halban PA, Weir GC, Donath MY.  2008.  Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation. J Clin Endocrinol Metab. 93(10):4065-74. Abstract
O'Rahilly S, Weir GC, Matthews DR.  2008.  An appreciation of Robert Turner. Diabetes. 57(11):2918-21.
Inada A, Kanamori H, Arai H, Akashi T, Araki M, Weir GC, Fukatsu A.  2008.  A model for diabetic nephropathy: advantages of the inducible cAMP early repressor transgenic mouse over the streptozotocin-induced diabetic mouse. J Cell Physiol. 215(2):383-91. Abstract
Marselli L, Thorne J, Ahn YB, Omer A, Sgroi DC, Libermann T, Otu HH, Sharma A, Bonner-Weir S, Weir GC.  2008.  Gene expression of purified beta-cell tissue obtained from human pancreas with laser capture microdissection. J Clin Endocrinol Metab. 93(3):1046-53. Abstract
Tonomura N, Shimizu A, Wang S, Yamada K, Tchipashvili V, Weir GC, Yang YG.  2008.  Pig islet xenograft rejection in a mouse model with an established human immune system. Xenotransplantation. 15(2):129-35. Abstract
Isshiki K, He Z, Maeno Y, Ma RC, Yasuda Y, Kuroki T, White GS, Patti ME, Weir GC, King GL.  2008.  Insulin regulates SOCS2 expression and the mitogenic effect of IGF-1 in mesangial cells. Kidney Int. 74(11):1434-43. Abstract
Xu J, Han J, Long YS, Lock J, Weir GC, Epstein PN, Liu YQ.  2008.  Malic enzyme is present in mouse islets and modulates insulin secretion. Diabetologia. 51(12):2281-9. Abstract
2007
King AJ, Fernandes JR, Hollister-Lock J, Nienaber CE, Bonner-Weir S, Weir GC.  2007.  Normal relationship of beta- and non-beta-cells not needed for successful islet transplantation. Diabetes. 56(9):2312-8. Abstract
Laybutt DR, Hawkins YC, Lock J, Lebet J, Sharma A, Bonner-Weir S, Weir GC.  2007.  Influence of diabetes on the loss of beta cell differentiation after islet transplantation in rats. Diabetologia. 50(10):2117-25. Abstract
Arikawa E, Ma RC, Isshiki K, Luptak I, He Z, Yasuda Y, Maeno Y, Patti ME, Weir GC, Harris RA, Zammit VA, Tian R, King GL.  2007.  Effects of insulin replacements, inhibitors of angiotensin, and PKCbeta's actions to normalize cardiac gene expression and fuel metabolism in diabetic rats. Diabetes. 56(5):1410-20. Abstract
Papas KK, Colton CK, Nelson RA, Rozak PR, Avgoustiniatos ES, Scott W. E. 3, Wildey GM, Pisania A, Weir GC, Hering BJ.  2007.  Human islet oxygen consumption rate and DNA measurements predict diabetes reversal in nude mice. Am J Transplant. 7(3):707-13. Abstract
Yatoh S, Akashi T, Chan PP, Kaneto H, Sharma A, Bonner-Weir S, Weir GC.  2007.  NeuroD and reaggregation induce beta-cell specific gene expression in cultured hepatocytes. Diabetes Metab Res Rev. 23(3):239-49. Abstract
Xu G, Kaneto H, Laybutt DR, Duvivier-Kali VF, Trivedi N, Suzuma K, King GL, Weir GC, Bonner-Weir S.  2007.  Downregulation of GLP-1 and GIP receptor expression by hyperglycemia: possible contribution to impaired incretin effects in diabetes. Diabetes. 56(6):1551-8. Abstract
Yatoh S, Dodge R, Akashi T, Omer A, Sharma A, Weir GC, Bonner-Weir S.  2007.  Differentiation of affinity-purified human pancreatic duct cells to beta-cells. Diabetes. 56(7):1802-9. Abstract
Weir GC, Bonner-Weir S.  2007.  A dominant role for glucose in beta cell compensation of insulin resistance. J Clin Invest. 117(1):81-3. Abstract
Ahn YB, Xu G, Marselli L, Toschi E, Sharma A, Bonner-Weir S, Sgroi DC, Weir GC.  2007.  Changes in gene expression in beta cells after islet isolation and transplantation using laser-capture microdissection. Diabetologia. 50(2):334-42. Abstract
Papas KK, Pisania A, Wu H, Weir GC, Colton CK.  2007.  A stirred microchamber for oxygen consumption rate measurements with pancreatic islets. Biotechnol Bioeng. 98(5):1071-82. Abstract
Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.  2007.  The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients. Diabetologia. 50(12):2486-94. Abstract
2006
Lopez-Avalos MD, Duvivier-Kali VF, Xu G, Bonner-Weir S, Sharma A, Weir GC.  2006.  Evidence for a role of the ubiquitin-proteasome pathway in pancreatic islets. Diabetes. 55(5):1223-31. Abstract
Xu G, Kaneto H, Lopez-Avalos MD, Weir GC, Bonner-Weir S.  2006.  GLP-1/exendin-4 facilitates beta-cell neogenesis in rat and human pancreatic ducts. Diabetes Res Clin Pract. 73(1):107-10.

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