Recent Publications from BIIC Members

Pancreatic beta cell mass PET imaging and quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in rodent models of diabetes.
Role of phospholipase Cε in physiological phosphoinositide signaling networks.
Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans.
Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol.
Epac2-dependent mobilization of intracellular Ca2+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in beta-cells of phospholipase C-epsilon knockout mice.
Hyperglucagonemia precedes a decline in insulin secretion and causes hyperglycemia in chronically glucose-infused rats.
Cytoplasmic Polyadenylation Element Binding Protein Deficiency Stimulates PTEN and Stat3 mRNA Translation and Induces Hepatic Insulin Resistance.
Prevalence of hepatitis C virus genotype 1a in Japan and correlation of mutations in the NS5A region and single-nucleotide polymorphism of interleukin-28B with the response to combination therapy with pegylated-interferon-alpha 2b and ribavirin.
Rates of insulin secretion in INS-1 cells are enhanced by coupling to anaplerosis and Kreb's cycle flux independent of ATP synthesis.
CT-PET weighted image fusion for separately scanned whole body rat.

You are hereRecent Publications of Members of the Boston Ithaca Islet Club

Recent Publications of Members of the Boston Ithaca Islet Club

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2008

Koulmanda M, Bhasin M, Hoffman L, Fan Z, Qipo A, Shi H, Bonner-Weir S, Putheti P, Degauque N, Libermann TA, Auchincloss H. J, Flier JS, Strom TB. 2008. Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice. Proc Natl Acad Sci U S A. 105(42):16242-7. Abstract

Elahi D, Egan JM, Shannon RP, Meneilly GS, Khatri A, Habener JF, Andersen DK. 2008. GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity (Silver Spring). 16(7):1501-9. Abstract

Holz GG, Heart E, Leech CA. 2008. Synchronizing Ca2+ and cAMP oscillations in pancreatic beta-cells: a role for glucose metabolism and GLP-1 receptors? Focus on "regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach" Am J Physiol Cell Physiol. 294(1):C4-6.

2007

Laybutt DR, Hawkins YC, Lock J, Lebet J, Sharma A, Bonner-Weir S, Weir GC. 2007. Influence of diabetes on the loss of beta cell differentiation after islet transplantation in rats. Diabetologia. 50(10):2117-25. Abstract

Deeney JT, Branstrom R, Corkey BE, Larsson O, Berggren PO. 2007. 3H-serotonin as a marker of oscillatory insulin secretion in clonal beta-cells (INS-1). FEBS Lett. 581(21):4080-4. Abstract

Kien CL, Blauwiekel R, Bunn JY, Jetton TL, Frankel WL, Holst JJ. 2007. Cecal infusion of butyrate increases intestinal cell proliferation in piglets. J Nutr. 137(4):916-22. Abstract

2006

Ubeda M, Rukstalis JM, Habener JF. 2006. Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity. J Biol Chem. 281(39):28858-64. Abstract

Bonner-Weir S, Sharma A. 2006. Are there pancreatic progenitor cells from which new islets form after birth? Nat Clin Pract Endocrinol Metab. 2(5):240-1.

Evgenov NV, Medarova Z, Dai G, Bonner-Weir S, Moore A. 2006. In vivo imaging of islet transplantation. Nat Med. 12(1):144-8. Abstract

2005

Hagman DK, Hays LB, Parazzoli SD, Poitout V. 2005. Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans. J Biol Chem. 280(37):32413-8. Abstract

Gaglia JL, Shapiro AM, Weir GC. 2005. Islet transplantation: progress and challenge. Arch Med Res. 36(3):273-80. Abstract

Hu Z, Dai Y, Prentki M, Chohnan S, Lane MD. 2005. A role for hypothalamic malonyl-CoA in the control of food intake. J Biol Chem. 280(48):39681-3. Abstract

Fukui K, Yang Q, Cao Y, Takahashi N, Hatakeyama H, Wang H, Wada J, Zhang Y, Marselli L, Nammo T, Yoneda K, Onishi M, Higashiyama S, Matsuzawa Y, Gonzalez FJ, Weir GC, Kasai H, Shimomura I, Miyagawa J, Wollheim CB, Yamagata K. 2005. The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation. Cell Metab. 2(6):373-84. Abstract

Iype T, Francis J, Garmey JC, Schisler JC, Nesher R, Weir GC, Becker TC, Newgard CB, Griffen SC, Mirmira RG. 2005. Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes. J Biol Chem. 280(17):16798-807. Abstract

2004

Lechner A, Yang YG, Blacken RA, Wang L, Nolan AL, Habener JF. 2004. No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivo. Diabetes. 53(3):616-23. Abstract

2003

Kamp F, Kizilbash N, Corkey BE, Berggren PO, Hamilton JA. 2003. Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism. Diabetes. 52(10):2526-31. Abstract

Heart E, Sung CK. 2003. Insulin-like and non-insulin-like selenium actions in 3T3-L1 adipocytes. J Cell Biochem. 88(4):719-31. Abstract

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