Recent Publications from BIIC Members

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You are hereRecent Publications of Members of the Boston Ithaca Islet Club

Recent Publications of Members of the Boston Ithaca Islet Club

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2008
Kebede M, Alquier T, Latour MG, Semache M, Tremblay C, Poitout V.  2008.  The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding. Diabetes. 57(9):2432-7. Abstract
Black AT, Gray JP, Shakarjian MP, Mishin V, Laskin DL, Heck DE, Laskin JD.  2008.  UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes. Toxicol Appl Pharmacol. 232(1):14-24. Abstract
Liu Z, Habener JF.  2008.  Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation. J Biol Chem. 283(13):8723-35. Abstract
Elahi D, Egan JM, Shannon RP, Meneilly GS, Khatri A, Habener JF, Andersen DK.  2008.  GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity (Silver Spring). 16(7):1501-9. Abstract
Holz GG, Chepurny OG, Schwede F.  2008.  Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors. Cell Signal. 20(1):10-20. Abstract
Holz GG, Heart E, Leech CA.  2008.  Synchronizing Ca2+ and cAMP oscillations in pancreatic beta-cells: a role for glucose metabolism and GLP-1 receptors? Focus on "regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach" Am J Physiol Cell Physiol. 294(1):C4-6.
de Koning EJ, Bonner-Weir S, Rabelink TJ.  2008.  Preservation of beta-cell function by targeting beta-cell mass. Trends Pharmacol Sci. 29(4):218-27. Abstract
2007
Morioka T, Asilmaz E, Hu J, Dishinger JF, Kurpad AJ, Elias CF, Li H, Elmquist JK, Kennedy RT, Kulkarni RN.  2007.  Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice. J Clin Invest. 117(10):2860-8. Abstract
Buhl ES, Neschen S, Yonemitsu S, Rossbacher J, Zhang D, Morino K, Flyvbjerg A, Perret P, Samuel V, Kim J, Cline GW, Petersen KF.  2007.  Increased hypothalamic-pituitary-adrenal axis activity and hepatic insulin resistance in low-birth-weight rats. Am J Physiol Endocrinol Metab. 293(5):E1451-8. Abstract
Xu G, Kaneto H, Laybutt DR, Duvivier-Kali VF, Trivedi N, Suzuma K, King GL, Weir GC, Bonner-Weir S.  2007.  Downregulation of GLP-1 and GIP receptor expression by hyperglycemia: possible contribution to impaired incretin effects in diabetes. Diabetes. 56(6):1551-8. Abstract
Madiraju SR, Poitout V.  2007.  G protein-coupled receptors and insulin secretion: 119 and counting. Endocrinology. 148(6):2598-600.
Pissios P, Ozcan U, Kokkotou E, Okada T, Liew CW, Liu S, Peters JN, Dahlgren G, Karamchandani J, Kudva YC, Kurpad AJ, Kennedy RT, Maratos-Flier E, Kulkarni RN.  2007.  Melanin concentrating hormone is a novel regulator of islet function and growth. Diabetes. 56(2):311-9. Abstract
Song DH, Getty-Kaushik L, Tseng E, Simon J, Corkey BE, Wolfe MM.  2007.  Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation. Gastroenterology. 133(6):1796-805. Abstract
Yano T, Liu Z, Donovan J, Thomas MK, Habener JF.  2007.  Stromal cell derived factor-1 (SDF-1)/CXCL12 attenuates diabetes in mice and promotes pancreatic beta-cell survival by activation of the prosurvival kinase Akt. Diabetes. 56(12):2946-57. Abstract
Chepurny OG, Holz GG.  2007.  A novel cyclic adenosine monophosphate responsive luciferase reporter incorporating a nonpalindromic cyclic adenosine monophosphate response element provides optimal performance for use in G protein coupled receptor drug discovery efforts. J Biomol Screen. 12(5):740-6. Abstract
Kulkarni RN, Kahn CR.  2007.  Ephs and ephrins keep pancreatic Beta cells connected. Cell. 129(2):241-3. Abstract
Latour MG, Alquier T, Oseid E, Tremblay C, Jetton TL, Luo J, Lin DC, Poitout V.  2007.  GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo. Diabetes. 56(4):1087-94. Abstract
2006
Wang L, Huang J, Saha P, Kulkarni RN, Hu M, Kim Y, Park K, Chan L, Rajan AS, Lee I, Moore DD.  2006.  Orphan receptor small heterodimer partner is an important mediator of glucose homeostasis. Mol Endocrinol. 20(11):2671-81. Abstract
List JF, He H, Habener JF.  2006.  Glucagon-like peptide-1 receptor and proglucagon expression in mouse skin. Regul Pept. 134(2-3):149-57. Abstract
Kang G, Chepurny OG, Malester B, Rindler MJ, Rehmann H, Bos JL, Schwede F, Coetzee WA, Holz GG.  2006.  cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells. J Physiol. 573(Pt 3):595-609. Abstract
Xu G, Kaneto H, Lopez-Avalos MD, Weir GC, Bonner-Weir S.  2006.  GLP-1/exendin-4 facilitates beta-cell neogenesis in rat and human pancreatic ducts. Diabetes Res Clin Pract. 73(1):107-10.
Getty-Kaushik L, Song DH, Boylan MO, Corkey BE, Wolfe MM.  2006.  Glucose-dependent insulinotropic polypeptide modulates adipocyte lipolysis and reesterification. Obesity (Silver Spring). 14(7):1124-31. Abstract
2005
Habener JF, Kemp DM, Thomas MK.  2005.  Minireview: transcriptional regulation in pancreatic development. Endocrinology. 146(3):1025-34. Abstract
Bates SH, Kulkarni RN, Seifert M, Myers M. G. J.  2005.  Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis. Cell Metab. 1(3):169-78. Abstract
Gragnoli C, Milord E, Habener JF.  2005.  Linkage study of the glucagon receptor gene with type 2 diabetes mellitus in Italians. Metabolism. 54(6):786-7. Abstract

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