Recent Publications from BIIC Members

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You are hereRecent Publications of Members of the Boston Ithaca Islet Club

Recent Publications of Members of the Boston Ithaca Islet Club

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2008
Larade K, Jiang Z, Zhang Y, Wang W, Bonner-Weir S, Zhu H, Bunn HF.  2008.  Loss of Ncb5or results in impaired fatty acid desaturation, lipoatrophy, and diabetes. J Biol Chem. 283(43):29285-91. Abstract
Koulmanda M, Bhasin M, Hoffman L, Fan Z, Qipo A, Shi H, Bonner-Weir S, Putheti P, Degauque N, Libermann TA, Auchincloss H. J, Flier JS, Strom TB.  2008.  Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice. Proc Natl Acad Sci U S A. 105(42):16242-7. Abstract
Akashi T, Shigematsu H, Hamamoto Y, Iwasaki H, Yatoh S, Bonner-Weir S, Akashi K, Weir GC.  2008.  Bone marrow or foetal liver cells fail to induce islet regeneration in diabetic Akita mice. Diabetes Metab Res Rev. 24(7):585-90. Abstract
Poitout V.  2008.  Glucolipotoxicity of the pancreatic beta-cell: myth or reality? Biochem Soc Trans. 36(Pt 5):901-4. Abstract
Boni-Schnetzler M, Thorne J, Parnaud G, Marselli L, Ehses JA, Kerr-Conte J, Pattou F, Halban PA, Weir GC, Donath MY.  2008.  Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation. J Clin Endocrinol Metab. 93(10):4065-74. Abstract
Leahy JL.  2008.  Mary, Mary, quite contrary, how do your beta-cells fail? Diabetes. 57(10):2563-4.
O'Rahilly S, Weir GC, Matthews DR.  2008.  An appreciation of Robert Turner. Diabetes. 57(11):2918-21.
Hinault C, Hu J, Maier BF, Mirmira RG, Kulkarni RN.  2008.  Differential expression of cell cycle proteins during ageing of pancreatic islet cells. Diabetes Obes Metab. 10 Suppl 4:136-46. Abstract
Bonner-Weir S, O'Brien TD.  2008.  Islets in type 2 diabetes: in honor of Dr. Robert C. Turner. Diabetes. 57(11):2899-904.
Poitout V, Robertson RP.  2008.  Glucolipotoxicity: fuel excess and beta-cell dysfunction. Endocr Rev. 29(3):351-66. Abstract
Maedler K, Schulthess FT, Bielman C, Berney T, Bonny C, Prentki M, Donath MY, Roduit R.  2008.  Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases. Faseb J. 22(6):1905-13. Abstract
de Koning EJ, Bonner-Weir S, Rabelink TJ.  2008.  Preservation of beta-cell function by targeting beta-cell mass. Trends Pharmacol Sci. 29(4):218-27. Abstract
2007
King AJ, Fernandes JR, Hollister-Lock J, Nienaber CE, Bonner-Weir S, Weir GC.  2007.  Normal relationship of beta- and non-beta-cells not needed for successful islet transplantation. Diabetes. 56(9):2312-8. Abstract
Laybutt DR, Hawkins YC, Lock J, Lebet J, Sharma A, Bonner-Weir S, Weir GC.  2007.  Influence of diabetes on the loss of beta cell differentiation after islet transplantation in rats. Diabetologia. 50(10):2117-25. Abstract
Arikawa E, Ma RC, Isshiki K, Luptak I, He Z, Yasuda Y, Maeno Y, Patti ME, Weir GC, Harris RA, Zammit VA, Tian R, King GL.  2007.  Effects of insulin replacements, inhibitors of angiotensin, and PKCbeta's actions to normalize cardiac gene expression and fuel metabolism in diabetic rats. Diabetes. 56(5):1410-20. Abstract
Madiraju SR, Poitout V.  2007.  G protein-coupled receptors and insulin secretion: 119 and counting. Endocrinology. 148(6):2598-600.
Han JR, Deng B, Sun J, Chen CG, Corkey BE, Kirkland JL, Ma J, Guo W.  2007.  Effects of dietary medium-chain triglyceride on weight loss and insulin sensitivity in a group of moderately overweight free-living type 2 diabetic Chinese subjects. Metabolism. 56(7):985-91. Abstract
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, Boutin P, Vincent D, Belisle A, Hadjadj S, Balkau B, Heude B, Charpentier G, Hudson TJ, Montpetit A, Pshezhetsky AV, Prentki M, Posner BI, Balding DJ, Meyre D, Polychronakos C, Froguel P.  2007.  A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature. 445(7130):881-5. Abstract
Page KA, Dejardin S, Kahn CR, Kulkarni RN, Herold KC, Inzucchi SE.  2007.  A patient with type B insulin resistance syndrome, responsive to immune therapy. Nat Clin Pract Endocrinol Metab. 3(12):835-40. Abstract
Yano T, Liu Z, Donovan J, Thomas MK, Habener JF.  2007.  Stromal cell derived factor-1 (SDF-1)/CXCL12 attenuates diabetes in mice and promotes pancreatic beta-cell survival by activation of the prosurvival kinase Akt. Diabetes. 56(12):2946-57. Abstract
Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.  2007.  The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients. Diabetologia. 50(12):2486-94. Abstract
Koulmanda M, Budo E, Bonner-Weir S, Qipo A, Putheti P, Degauque N, Shi H, Fan Z, Flier JS, Auchincloss H. J, Zheng XX, Strom TB.  2007.  Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts. Proc Natl Acad Sci U S A. 104(32):13074-9. Abstract
Xue B, Kim YB, Lee A, Toschi E, Bonner-Weir S, Kahn CR, Neel BG, Kahn BB.  2007.  Protein-tyrosine phosphatase 1B deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance. J Biol Chem. 282(33):23829-40. Abstract
2006
Ubeda M, Rukstalis JM, Habener JF.  2006.  Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity. J Biol Chem. 281(39):28858-64. Abstract
Evgenov NV, Medarova Z, Pratt J, Pantazopoulos P, Leyting S, Bonner-Weir S, Moore A.  2006.  In vivo imaging of immune rejection in transplanted pancreatic islets. Diabetes. 55(9):2419-28. Abstract

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