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Recent Publications of Members of the Boston Ithaca Islet Club


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2008
Larade K, Jiang Z, Zhang Y, Wang W, Bonner-Weir S, Zhu H, Bunn HF.  2008.  Loss of Ncb5or results in impaired fatty acid desaturation, lipoatrophy, and diabetes. J Biol Chem. 283(43):29285-91. Abstract
Leahy JL.  2008.  Mary, Mary, quite contrary, how do your beta-cells fail? Diabetes. 57(10):2563-4.
Nolan CJ, Prentki M.  2008.  The islet beta-cell: fuel responsive and vulnerable. Trends Endocrinol Metab. 19(8):285-91. Abstract
Bonner-Weir S, Inada A, Yatoh S, Li WC, Aye T, Toschi E, Sharma A.  2008.  Transdifferentiation of pancreatic ductal cells to endocrine beta-cells. Biochem Soc Trans. 36(Pt 3):353-6. Abstract
Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS.  2008.  Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. Embo J. 27(2):433-46. Abstract
Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS.  2008.  Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. Embo J. 27(2):433-46. Abstract
Danial NN, Walensky LD, Zhang CY, Choi CS, Fisher JK, Molina AJ, Datta SR, Pitter KL, Bird GH, Wikstrom JD, Deeney JT, Robertson K, Morash J, Kulkarni A, Neschen S, Kim S, Greenberg ME, Corkey BE, Shirihai OS, Shulman GI, Lowell BB, Korsmeyer SJ.  2008.  Dual role of proapoptotic BAD in insulin secretion and beta cell survival. Nat Med. 14(2):144-53. Abstract
Danial NN, Walensky LD, Zhang CY, Choi CS, Fisher JK, Molina AJ, Datta SR, Pitter KL, Bird GH, Wikstrom JD, Deeney JT, Robertson K, Morash J, Kulkarni A, Neschen S, Kim S, Greenberg ME, Corkey BE, Shirihai OS, Shulman GI, Lowell BB, Korsmeyer SJ.  2008.  Dual role of proapoptotic BAD in insulin secretion and beta cell survival. Nat Med. 14(2):144-53. Abstract
2007
Madiraju SR, Poitout V.  2007.  G protein-coupled receptors and insulin secretion: 119 and counting. Endocrinology. 148(6):2598-600.
Przybytkowski E, Joly E, Nolan CJ, Hardy S, Francoeur AM, Langelier Y, Prentki M.  2007.  Upregulation of cellular triacylglycerol - free fatty acid cycling by oleate is associated with long-term serum-free survival of human breast cancer cells. Biochem Cell Biol. 85(3):301-10. Abstract
Pi J, Bai Y, Zhang Q, Wong V, Floering LM, Daniel K, Reece JM, Deeney JT, Andersen ME, Corkey BE, Collins S.  2007.  Reactive oxygen species as a signal in glucose-stimulated insulin secretion. Diabetes. 56(7):1783-91. Abstract
Pongratz RL, Kibbey RG, Shulman GI, Cline GW.  2007.  Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion. J Biol Chem. 282(1):200-7. Abstract
Branstrom R, Leibiger IB, Leibiger B, Klement G, Nilsson J, Arhem P, Aspinwall CA, Corkey BE, Larsson O, Berggren PO.  2007.  Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif. Diabetologia. 50(8):1670-7. Abstract
Kibbey RG, Pongratz RL, Romanelli AJ, Wollheim CB, Cline GW, Shulman GI.  2007.  Mitochondrial GTP regulates glucose-stimulated insulin secretion. Cell Metab. 5(4):253-64. Abstract
2006
Nolan CJ, Leahy JL, Delghingaro-Augusto V, Moibi J, Soni K, Peyot ML, Fortier M, Guay C, Lamontagne J, Barbeau A, Przybytkowski E, Joly E, Masiello P, Wang S, Mitchell GA, Prentki M.  2006.  Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling. Diabetologia. 49(9):2120-30. Abstract
Wang L, Huang J, Saha P, Kulkarni RN, Hu M, Kim Y, Park K, Chan L, Rajan AS, Lee I, Moore DD.  2006.  Orphan receptor small heterodimer partner is an important mediator of glucose homeostasis. Mol Endocrinol. 20(11):2671-81. Abstract
Nishimura W, Kondo T, Salameh T, El Khattabi I, Dodge R, Bonner-Weir S, Sharma A.  2006.  A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev Biol. 293(2):526-39. Abstract
Nolan CJ, Madiraju MS, Delghingaro-Augusto V, Peyot ML, Prentki M.  2006.  Fatty acid signaling in the beta-cell and insulin secretion. Diabetes. 55 Suppl 2:S16-23. Abstract
2005
Habener JF, Kemp DM, Thomas MK.  2005.  Minireview: transcriptional regulation in pancreatic development. Endocrinology. 146(3):1025-34. Abstract
Holz GG, Chepurny OG.  2005.  Diabetes outfoxed by GLP-1? Sci STKE. 2005(268):pe2. Abstract
Getty-Kaushik L, Richard AM, Corkey BE.  2005.  Glucose-dependent insulin modulation of oscillatory lipolysis in perifused rat adipocytes. Obes Res. 13(12):2058-65. Abstract
Fukui K, Yang Q, Cao Y, Takahashi N, Hatakeyama H, Wang H, Wada J, Zhang Y, Marselli L, Nammo T, Yoneda K, Onishi M, Higashiyama S, Matsuzawa Y, Gonzalez FJ, Weir GC, Kasai H, Shimomura I, Miyagawa J, Wollheim CB, Yamagata K.  2005.  The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation. Cell Metab. 2(6):373-84. Abstract
Iype T, Francis J, Garmey JC, Schisler JC, Nesher R, Weir GC, Becker TC, Newgard CB, Griffen SC, Mirmira RG.  2005.  Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes. J Biol Chem. 280(17):16798-807. Abstract

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