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Recent Publications of Members of the Boston Ithaca Islet Club


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2009
Torii S, Saito N, Kawano A, Hou N, Ueki K, Kulkarni RN, Takeuchi T.  2009.  Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth. Diabetes. 58(3):682-92. Abstract
Pi J, Bai Y, Daniel KW, Liu D, Lyght O, Edelstein D, Brownlee M, Corkey BE, Collins S.  2009.  Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function. Endocrinology. 150(7):3040-8. Abstract
2008
Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS.  2008.  Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. Embo J. 27(2):433-46. Abstract
Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS.  2008.  Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. Embo J. 27(2):433-46. Abstract
Holz GG, Heart E, Leech CA.  2008.  Synchronizing Ca2+ and cAMP oscillations in pancreatic beta-cells: a role for glucose metabolism and GLP-1 receptors? Focus on "regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach" Am J Physiol Cell Physiol. 294(1):C4-6.
2007
Moibi JA, Gupta D, Jetton TL, Peshavaria M, Desai R, Leahy JL.  2007.  Peroxisome proliferator-activated receptor-gamma regulates expression of PDX-1 and NKX6.1 in INS-1 cells. Diabetes. 56(1):88-95. Abstract
Pissios P, Ozcan U, Kokkotou E, Okada T, Liew CW, Liu S, Peters JN, Dahlgren G, Karamchandani J, Kudva YC, Kurpad AJ, Kennedy RT, Maratos-Flier E, Kulkarni RN.  2007.  Melanin concentrating hormone is a novel regulator of islet function and growth. Diabetes. 56(2):311-9. Abstract
Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.  2007.  The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients. Diabetologia. 50(12):2486-94. Abstract
Kulkarni RN, Kahn CR.  2007.  Ephs and ephrins keep pancreatic Beta cells connected. Cell. 129(2):241-3. Abstract
2005
Hu L, Deeney JT, Nolan CJ, Peyot ML, Ao A, Richard AM, Luc E, Faergeman NJ, Knudsen J, Guo W, Sorhede-Winzell M, Prentki M, Corkey BE.  2005.  Regulation of lipolytic activity by long-chain acyl-coenzyme A in islets and adipocytes. Am J Physiol Endocrinol Metab. 289(6):E1085-92. Abstract
Inada A, Nagai K, Arai H, Miyazaki J, Nomura K, Kanamori H, Toyokuni S, Yamada Y, Bonner-Weir S, Weir GC, Fukatsu A, Seino Y.  2005.  Establishment of a diabetic mouse model with progressive diabetic nephropathy. Am J Pathol. 167(2):327-36. Abstract
2004
Ogawa N, List JF, Habener JF, Maki T.  2004.  Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4. Diabetes. 53(7):1700-5. Abstract
Liu YQ, Moibi JA, Leahy JL.  2004.  Chronic high glucose lowers pyruvate dehydrogenase activity in islets through enhanced production of long chain acyl-CoA: prevention of impaired glucose oxidation by enhanced pyruvate recycling through the malate-pyruvate shuttle. J Biol Chem. 279(9):7470-5. Abstract

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