Recent Publications from BIIC Members

Glucose activates free fatty acid receptor 1 gene transcription via phosphatidylinositol-3-kinase-dependent O-GlcNAcylation of pancreas-duodenum homeobox-1.
Exogenous insulin enhances glucose-stimulated insulin response in healthy humans independent of changes in free fatty acids.
Loss of glucagon-like peptide-2-induced proliferation following intestinal epithelial insulin-like growth factor-1-receptor deletion.
Pancreatic beta cell mass PET imaging and quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in rodent models of diabetes.
Role of phospholipase Cε in physiological phosphoinositide signaling networks.
Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans.
Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol.
Epac2-dependent mobilization of intracellular Ca2+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in beta-cells of phospholipase C-epsilon knockout mice.
Hyperglucagonemia precedes a decline in insulin secretion and causes hyperglycemia in chronically glucose-infused rats.
Cytoplasmic Polyadenylation Element Binding Protein Deficiency Stimulates PTEN and Stat3 mRNA Translation and Induces Hepatic Insulin Resistance.

You are hereRecent Publications of Members of the Boston Ithaca Islet Club

Recent Publications of Members of the Boston Ithaca Islet Club

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2009

Kawamori D, Kurpad AJ, Hu J, Liew CW, Shih JL, Ford EL, Herrera PL, Polonsky KS, McGuinness OP, Kulkarni RN. 2009. Insulin signaling in alpha cells modulates glucagon secretion in vivo. Cell Metab. 9(4):350-61. Abstract

2007

Zhang D, Liu ZX, Choi CS, Tian L, Kibbey R, Dong J, Cline GW, Wood PA, Shulman GI. 2007. Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance. Proc Natl Acad Sci U S A. 104(43):17075-80. Abstract

Neschen S, Morino K, Dong J, Wang-Fischer Y, Cline GW, Romanelli AJ, Rossbacher JC, Moore IK, Regittnig W, Munoz DS, Kim JH, Shulman GI. 2007. n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner. Diabetes. 56(4):1034-41. Abstract

2006

Nolan CJ, Leahy JL, Delghingaro-Augusto V, Moibi J, Soni K, Peyot ML, Fortier M, Guay C, Lamontagne J, Barbeau A, Przybytkowski E, Joly E, Masiello P, Wang S, Mitchell GA, Prentki M. 2006. Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling. Diabetologia. 49(9):2120-30. Abstract

2003

Tien ES, Gray JP, Peters JM, Vanden Heuvel JP. 2003. Comprehensive gene expression analysis of peroxisome proliferator-treated immortalized hepatocytes: identification of peroxisome proliferator-activated receptor alpha-dependent growth regulatory genes. Cancer Res. 63(18):5767-80. Abstract

Gray JP, Leas TL, Obert E, Brown D, Clark GC, Vanden Heuvel JP. 2003. Evidence of aryl hydrocarbon receptor ligands in Presque Isle Bay of Lake Erie. Aquat Toxicol. 64(3):343-58. Abstract

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