You are hereRecent Publications of Members of the Boston Ithaca Islet Club

Recent Publications of Members of the Boston Ithaca Islet Club


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2007
Zhang D, Liu ZX, Choi CS, Tian L, Kibbey R, Dong J, Cline GW, Wood PA, Shulman GI.  2007.  Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance. Proc Natl Acad Sci U S A. 104(43):17075-80. Abstract
Choi CS, Savage DB, Abu-Elheiga L, Liu ZX, Kim S, Kulkarni A, Distefano A, Hwang YJ, Reznick RM, Codella R, Zhang D, Cline GW, Wakil SJ, Shulman GI.  2007.  Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity. Proc Natl Acad Sci U S A. 104(42):16480-5. Abstract
Morioka T, Asilmaz E, Hu J, Dishinger JF, Kurpad AJ, Elias CF, Li H, Elmquist JK, Kennedy RT, Kulkarni RN.  2007.  Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice. J Clin Invest. 117(10):2860-8. Abstract
Buhl ES, Neschen S, Yonemitsu S, Rossbacher J, Zhang D, Morino K, Flyvbjerg A, Perret P, Samuel V, Kim J, Cline GW, Petersen KF.  2007.  Increased hypothalamic-pituitary-adrenal axis activity and hepatic insulin resistance in low-birth-weight rats. Am J Physiol Endocrinol Metab. 293(5):E1451-8. Abstract
Okada T, Liew CW, Hu J, Hinault C, Michael MD, Krtzfeldt J, Yin C, Holzenberger M, Stoffel M, Kulkarni RN.  2007.  Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance. Proc Natl Acad Sci U S A. 104(21):8977-82. Abstract
Kulkarni RN, Kahn CR.  2007.  Ephs and ephrins keep pancreatic Beta cells connected. Cell. 129(2):241-3. Abstract
Guo W, Pirtskhalava T, Tchkonia T, Xie W, Thomou T, Han J, Wang T, Wong S, Cartwright A, Hegardt FG, Corkey BE, Kirkland JL.  2007.  Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity. Am J Physiol Endocrinol Metab. 292(4):E1041-51. Abstract
Gray S, Wang B, Orihuela Y, Hong EG, Fisch S, Haldar S, Cline GW, Kim JK, Peroni OD, Kahn BB, Jain MK.  2007.  Regulation of gluconeogenesis by Kruppel-like factor 15. Cell Metab. 5(4):305-12. Abstract
2006
Spoor DC, Martineau LC, Leduc C, Benhaddou-Andaloussi A, Meddah B, Harris C, Burt A, Fraser MH, Coonishish J, Joly E, Cuerrier A, Bennett SA, Johns T, Prentki M, Arnason JT, Haddad PS.  2006.  Selected plant species from the Cree pharmacopoeia of northern Quebec possess anti-diabetic potential. Can J Physiol Pharmacol. 84(8-9):847-58. Abstract
2005
Landa L. R. J, Harbeck M, Kaihara K, Chepurny O, Kitiphongspattana K, Graf O, Nikolaev VO, Lohse MJ, Holz GG, Roe MW.  2005.  Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 beta-cell line. J Biol Chem. 280(35):31294-302. Abstract
Hagman DK, Hays LB, Parazzoli SD, Poitout V.  2005.  Palmitate inhibits insulin gene expression by altering PDX-1 nuclear localization and reducing MafA expression in isolated rat islets of Langerhans. J Biol Chem. 280(37):32413-8. Abstract
Park SY, Cho YR, Finck BN, Kim HJ, Higashimori T, Hong EG, Lee MK, Danton C, Deshmukh S, Cline GW, Wu JJ, Bennett AM, Rothermel B, Kalinowski A, Russell KS, Kim YB, Kelly DP, Kim JK.  2005.  Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver. Diabetes. 54(9):2514-24. Abstract
Gaglia JL, Shapiro AM, Weir GC.  2005.  Islet transplantation: progress and challenge. Arch Med Res. 36(3):273-80. Abstract
Leahy JL.  2005.  Pathogenesis of type 2 diabetes mellitus. Arch Med Res. 36(3):197-209. Abstract
Schisler JC, Jensen PB, Taylor DG, Becker TC, Knop FK, Takekawa S, German M, Weir GC, Lu D, Mirmira RG, Newgard CB.  2005.  The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells. Proc Natl Acad Sci U S A. 102(20):7297-302. Abstract
2003
Guo W, Lei T, Wang T, Corkey BE, Han J.  2003.  Octanoate inhibits triglyceride synthesis in 3T3-L1 and human adipocytes. J Nutr. 133(8):2512-8. Abstract

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