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Recent Publications of Members of the Boston Ithaca Islet Club


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2009
Guay C, Goudreault D, Schanzer W, Flenker U, Ayotte C.  2009.  Excretion of norsteroids' phase II metabolites of different origin in human. Steroids. 74(3):350-8. Abstract
Heart E, Cline GW, Collis LP, Pongratz RL, Gray JP, Smith PJ.  2009.  Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion. Am J Physiol Endocrinol Metab. 296(6):E1354-62. Abstract
Harangi M, Mirdamadi HZ, Seres I, Sztanek F, Molnar M, Kassai A, Derdak Z, Illyes L, Paragh G.  2009.  Atorvastatin effect on the distribution of high-density lipoprotein subfractions and human paraoxonase activity. Transl Res. 153(4):190-8. Abstract
Weir GC, Koulamnda M.  2009.  Control of inflammation with alpha1-antitrypsin: a potential treatment for islet transplantation and new-onset type 1 diabetes. Curr Diab Rep. 9(2):100-2.
2008
Twig G, Hyde B, Shirihai OS.  2008.  Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view. Biochim Biophys Acta. 1777(9):1092-7. Abstract
Poitout V.  2008.  Glucolipotoxicity of the pancreatic beta-cell: myth or reality? Biochem Soc Trans. 36(Pt 5):901-4. Abstract
Prentki M, Madiraju SR.  2008.  Glycerolipid metabolism and signaling in health and disease. Endocr Rev. 29(6):647-76. Abstract
Boni-Schnetzler M, Thorne J, Parnaud G, Marselli L, Ehses JA, Kerr-Conte J, Pattou F, Halban PA, Weir GC, Donath MY.  2008.  Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation. J Clin Endocrinol Metab. 93(10):4065-74. Abstract
Leahy JL.  2008.  Mary, Mary, quite contrary, how do your beta-cells fail? Diabetes. 57(10):2563-4.
Nolan CJ, Prentki M.  2008.  The islet beta-cell: fuel responsive and vulnerable. Trends Endocrinol Metab. 19(8):285-91. Abstract
Gupta D, Jetton TL, Mortensen RM, Duan SZ, Peshavaria M, Leahy JL.  2008.  In vivo and in vitro studies of a functional peroxisome proliferator-activated receptor gamma response element in the mouse pdx-1 promoter. J Biol Chem. 283(47):32462-70. Abstract
Hinault C, Hu J, Maier BF, Mirmira RG, Kulkarni RN.  2008.  Differential expression of cell cycle proteins during ageing of pancreatic islet cells. Diabetes Obes Metab. 10 Suppl 4:136-46. Abstract
Bonner-Weir S, O'Brien TD.  2008.  Islets in type 2 diabetes: in honor of Dr. Robert C. Turner. Diabetes. 57(11):2899-904.
Poitout V, Robertson RP.  2008.  Glucolipotoxicity: fuel excess and beta-cell dysfunction. Endocr Rev. 29(3):351-66. Abstract
Liu Z, Habener JF.  2008.  Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation. J Biol Chem. 283(13):8723-35. Abstract
Wang Y, Gray JP, Mishin V, Heck DE, Laskin DL, Laskin JD.  2008.  Role of cytochrome P450 reductase in nitrofurantoin-induced redox cycling and cytotoxicity. Free Radic Biol Med. 44(6):1169-79. Abstract
Kang G, Leech CA, Chepurny OG, Coetzee WA, Holz GG.  2008.  Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cells. J Physiol. 586(5):1307-19. Abstract
Marselli L, Thorne J, Ahn YB, Omer A, Sgroi DC, Libermann T, Otu HH, Sharma A, Bonner-Weir S, Weir GC.  2008.  Gene expression of purified beta-cell tissue obtained from human pancreas with laser capture microdissection. J Clin Endocrinol Metab. 93(3):1046-53. Abstract
Tonomura N, Shimizu A, Wang S, Yamada K, Tchipashvili V, Weir GC, Yang YG.  2008.  Pig islet xenograft rejection in a mouse model with an established human immune system. Xenotransplantation. 15(2):129-35. Abstract
Suszynski TM, Wildey GM, Falde EJ, Cline GW, Maynard KS, Ko N, Sotiris J, Naji A, Hering BJ, Papas KK.  2008.  The ATP/DNA ratio is a better indicator of islet cell viability than the ADP/ATP ratio. Transplant Proc. 40(2):346-50. Abstract
Maedler K, Schulthess FT, Bielman C, Berney T, Bonny C, Prentki M, Donath MY, Roduit R.  2008.  Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases. Faseb J. 22(6):1905-13. Abstract
Bonner-Weir S, Inada A, Yatoh S, Li WC, Aye T, Toschi E, Sharma A.  2008.  Transdifferentiation of pancreatic ductal cells to endocrine beta-cells. Biochem Soc Trans. 36(Pt 3):353-6. Abstract
Elahi D, Egan JM, Shannon RP, Meneilly GS, Khatri A, Habener JF, Andersen DK.  2008.  GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity (Silver Spring). 16(7):1501-9. Abstract
Holz GG, Chepurny OG, Schwede F.  2008.  Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors. Cell Signal. 20(1):10-20. Abstract
Holz GG, Heart E, Leech CA.  2008.  Synchronizing Ca2+ and cAMP oscillations in pancreatic beta-cells: a role for glucose metabolism and GLP-1 receptors? Focus on "regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach" Am J Physiol Cell Physiol. 294(1):C4-6.

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